| ORIGINAL ARTICLE |
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| Year : 2022 | Volume
: 1
| Issue : 2 | Page : 64-69 |
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A preliminary pharmacognostical and physicochemical evaluation of Guduchyadi Vati: A novel herbal formulation for juvenile diabetes
Vedanshi A Limbachiya1, Sagar M Bhinde1, C. R. Harisha2, Vinay J Shukla3
1 Department of Kaumarbhritya, Institute of Teaching & Research in Ayurveda, Jamnagar, Gujarat, India
2 Department of Pharmacognosy, Institute of Teaching & Research in Ayurveda, Jamnagar, Gujarat, India
3 Department of Pharmaceutics, Institute of Teaching & Research in Ayurveda, Jamnagar, Gujarat, India
Correspondence Address:
Dr. Vedanshi A Limbachiya
Department of Kaumarbhritya, Institute of Teaching & Research in Ayurveda, PG Girls’ Hostel, Institute of Teaching and Research in Ayurveda, Jamnagar 361008, Gujarat
India
 Source of Support: None, Conflict of Interest: None
DOI: 10.4103/jahas.jahas_1_23
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Background: Most of Ayurveda medicines are effective, but they require standardization. Standardization of an herbal formulation is essential to assess the quality of drugs, based on the physicochemical standards and pharmacognostical parameters. Maintaining the quality of any traditional formulation or pharmaceutical product is need of hours to ensure the safety of the patient. A pharmaceutical product that does not meet the required standards can cause a serious threat to public health and safety. Here, an attempt has been made to set preliminary pharmacognostical and pharmaceutical parameters along with high-performance thin-layer chromatography (HPTLC) of one of the novel herbal formulations named Guduchyadi Vati for the treatment of JatajaPrameha (juvenile diabetes). Objective: To evaluate and establish the pharmacognostical and physicochemical parameters of Guduchyadi Vati.Materials and Methods: Preauthenticated raw drugs were procured and prepared at the Pharmacy, Institute of Teaching and Research in Ayurveda (ITRA), Jamnagar. Organoleptic parameters and microscopic analysis of Guduchyadi Vati were done at Pharmacognosy Department, ITRA, Jamnagar. Physicochemical analysis of tablet and HPTLC were done at the Pharmaceutical Laboratory, ITRA, Jamnagar. Results: Microscopic features of Guduchyadi Vati were cross-checked with The Ayurvedic Pharmacopoeia of India standards of individual ingredients, and it was found that all characteristics remain intake. In pharmaceutical parameters, the pH value was 6.5, water-soluble extract was 25.55%, alcohol-soluble extract was 10.32%, ash value was 12.37%, and loss on drying was 0.16%w/w. HPTLC at 254 and 366 nm showed 3 and 16 spots, respectively. Conclusions: This study generated preliminary data on pharmacognostical and physicochemical parameters of Guduchyadi Vati. These fingerprints could be useful for future researchers to the reproduction of this formulation as quality control parameters for Guduchyadi Vati are not available in The Ayurvedic Pharmacopoeia of India or the public domain. |
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